RNA Structure
Learning Objectives: Understand the structure of RNA, differentiate between the three main types of RNA (mRNA, tRNA, rRNA), and compare RNA with DNA.


What is RNA?
Ribonucleic Acid (RNA) is a single-stranded nucleic acid molecule that plays crucial roles in gene expression and protein synthesis. Unlike DNA, which stores genetic information, RNA acts as a messenger and functional molecule that helps translate genetic instructions into proteins.
Basic Structure of RNA:
- Sugar: Ribose (contains a hydroxyl group at the 2' position)
- Phosphate Group: Links nucleotides together via phosphodiester bonds
- Nitrogenous Bases: Adenine (A), Guanine (G), Cytosine (C), and Uracil (U) - NOT Thymine!
- Structure: Single-stranded (can fold into complex 3D shapes)
RNA vs DNA: Key Differences
Interactive visualization — available in the full lesson
3D Model: RNA Strand & Nucleotide
Interactive visualization — available in the full lesson
● Ribose Backbone
● 2' Hydroxyl (OH)
● Uracil Base
● Adenine Base
Notice the single-stranded helical structure and the presence of Uracil instead of Thymine.