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The Internal Environment of the Body: Blood and Immunity

Biology Grade 8 Difficulty 2/5

Beginning of the lesson

🩸 The Internal Environment of the Body

Blood & Immunity — A Chemistry Perspective

Grade 8 Biology | Understanding What Blood Is Made Of and How It Carries Oxygen


Part 1: What Is Blood Plasma Made Of?

The Liquid Part of Blood

If you let a tube of blood sit still (or spin it in a centrifuge), it separates into layers. The top layer — a light amber (straw-colored) liquid — is blood plasma. It makes up about 55% of your total blood volume. The remaining 45% consists of red blood cells, white blood cells, and platelets.

Key Definition: Blood plasma is the liquid matrix of blood in which cells and cell fragments are suspended. It is roughly 90–92% water, but the remaining 8–10% contains dissolved substances that are absolutely critical for life.
Interactive visualization — available in the full lesson

The Dissolved Solutes in Plasma

Even though water dominates, the dissolved solutes are what make plasma so important. Let's break them down:

🧬 Proteins (~7%)

The three major plasma proteins are:

  • Albumins (~60% of plasma proteins): Maintain osmotic pressure — they keep water from leaking out of blood vessels into surrounding tissues.
  • Globulins: The second most abundant type. Alpha and beta globulins transport lipids (fats), metal ions, and fat-soluble vitamins. Gamma globulins are antibodies used in immunity.
  • Fibrinogen: Essential for blood clotting. When you get a cut, fibrinogen is converted to fibrin threads that form a mesh to stop bleeding.

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In the full lesson

  • The complete explanation
  • Worked examples
  • Common mistakes and how to avoid them
  • Test questions: 130
  • AI tutor that answers questions about the topic
  • Progress tracking for students, parents and teachers